This study was designed to evaluate the neuroprotective activity of ethanol extract of Pongamia pinnata stem bark in monosodium glutamate-induced neurotoxicity in rats. Neurotoxicity was induced by intraperitoneal injection of monosodium glutamate 2 g per kg body weight daily for 7 days. Ethanol extract of Pongamia pinnata stem bark (200 and 400 mg/kg) was administered orally after 1 h of monos...

Pongamia pinnata is a marsh growing Indian tree. Its seeds are used in febrile and inflammatory diseases in Indian system of medicine. Previous preliminary studies with ethanolic seed extract of this plant had exhibited an anti-inflammatory effect in rat. Different solvent fractionated extracts were evaluated in the present study for anti-inflammatory effect in chemically induced paw inflammati...

Studies on organic seed fortification with Jatropha curcas and Pongamia pinnata using ‘Panchagavya ’at one, two, three, four and five per cent concentrations with the three different soaking durations revealed that Panchagavya at 2 and 5% with the soaking duration of 16 and 8 h were superior than the control and other concentrations in terms of germination and seedling vigour for Jatropha curca...

The hepato protective effect of the methanolic extract of Pongamia Pinnata flowers, an indigenous. Ayurvedic medicinal plant in India, was studied in rats with lead acetate induced hepatotoxicity. Administering 160 mg/kg b.wt/day of lead acetate for 90 days to male albino rats resulted in significantly elevated levels of ALT, AST, GGT, ALP, Bilirubin and protein were also observed on lead aceta...

Original article Hyperammonemia Cholesterol Ammonia Triglycerides Phospholipids Free fatty acids Pongamia pinnata

The present study was carried out with the bark of Pongamia pinnata Linn, belonging to the family Fabaceae. It is one of the fast growing, glabrous, deciduous tree and has recently gained importance as a commercial source of furanoflavones like kaempferol, karanjin. Methanolic extract of Pongamia pinnata was subjected to phytochemical screening. Gut motility activity was produced by oral admini...

Plants fumigated with 40ppbv, 80 ppbv and 120ppbv concentrations of O3 exhibited significant reduction in total chlorophyll content, RuBP carboxylase activity and net photosynthesis. The reduction in total chlorophyll activity ranged from 12 to 36% in Bauhinia variegata, 11 to 35% in Ficus infectoria and 3 to 26% in Pongamia pinnata on fumigation with O3, while the RuBP carboxylase activity was...

The effects of Pongamia pinnata on stem cells have rarely been tested. This study aimed to evaluate the effects of the extract of Pongamia pinnata on the morphology and proliferation potential of the human gingival stem cells. Stem cells obtained from gingiva were cultured in a growth medium in the presence of Pongamia pinnata methanolic extract (PPT) at concentrations ranging from 0.001% to 1%...

The study was aimed at assessing the effects of indigenous Plant Growth Promoting Bacterium (PGPB) on the legume Pongamia pinnata in the degraded soil of the Nanmangalam Reserve Forest (NRF) under nursery conditions. In total, 160 diazotrophs were isolated from three different nitrogen-free semi-solid media (LGI, Nfb, and JMV). Amongst these isolates, Pseudomonas aeruginosa RRALC3 exhibited the...

A rapid, simple and specific reversed-phase HPLC method has been developed for analysis of karanjin in Pongamia pinnata Linn. leaves. HPLC analysis was performed on a C(18) column using an 85:13.5:1.5 (v/v) mixtures of methanol, water and acetic acid as isocratic mobile phase at a flow rate of 1 ml/min. UV detection was at 300 nm. The method was validated for accuracy, precision, linearity, spe...